So in the linked paper, novel is used to describe those mutations that were not previously reported, to the knowledge of the authors. Answered by Editage Insights Novelty definition is - something new or unusual. 8 years ago It's usually used to describe research that has identified phenomena or developed techniques/materials that haven't been previously reported in the literature. What is the difference between a research paper and a review paper? By exchanging depth of research for breadth of claims, researchers may be at risk of compromising the robustness of the work. [CDATA[// >